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In rodent, the ability of opioid to promote analgesia to different type of stimuli could be measured using numerous behavioral paradigms including hot-plate test and tail-flick for thermal nociception (Barrot, 2012)

The authors thank two reviewers whose highly professional and constructive comments helped us substantially improve the quality of the paper

Antioxidants 8:384

Platelet-secreted chemokine platelet factor 4 (PF4/CXCL4) improves age-related cognitive impairment through hippocampal neurogenesis, which is the key to delaying the aging of the brain
