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This complex induces superoxide production and mitochondrial stress, thereby overcoming resistance to both radiation and chemotherapy [240]

10.1016/j.celrep.2020.02.049 68 FernagutP

Notably, ATP activates P2 receptors on NK cells, inducing IL-22 secretion, which is critical for efficient liver regeneration

Meanwhile, cytokines including TNF-, IL-1, IFN-, and IL-6 could promote the activation of XO, resulting in the production of ROS (73)

Therefore, further research is needed to fully understand and harness the potential of O-GlcNAcylation in the treatment of ischemic stroke

Ahmad RS, Hussain MB, Sultan MT, Arshad MS, Waheed M, Shariati MA, et al