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Pickart, Loren, and Anna Margolina

has demonstrated that asperuloside, a natural iridoid glycoside, exerts protective effects against osteoporosis by promoting autophagy and regulating Nrf2 activation, further supporting the role of this pathway as a therapeutic target [64]

Boisvert, M

The enzyme glutamine synthetase binds ammonia to glutamate to form L-Glutamine, effectively trapping the toxic nitrogen

Consequently, these experimental outcomes are consistent with a model in which the ROS-MAPK/Erk1/2 pathway may play a crucial role in mediating the hepatocyte toxicity induced by excessive CGA

3-hydroxy androstane [16,17- C ](6methyl, 2-1-hydroxyisopropene-1-yl) 4,5,6- H -pyran